Particle Growth of Porous Spherical Hydroxyapatite by Two-step Phosphoration

Yasukiyo UEDA*, Hirokazu MIYAKE, Hidemitsu KASAHARA and Mitsunobu AOYAMA

Department of Chemical Science and Engineering, Faculty of Engineering, Kobe University; Rokkodai, Nada, Kobe-shi 657-8501 Japan
Research and Development Division, Maruo Calcium Co., Ltd.; Nishioka, Uozumi, Akashi-shi 674-0084 Japan

Low crystalline porous aggregates of hydroxyapatite (HAp) were prepared with colloidal calcium carbonate and phosphoric acid. Particle size and specific surface area of spherical HAp aggregates were controllable by two-step phosphoration with colloidal calcium carbonate and ammonium dihydrogenphosphate using low crystalline porous aggregates of HAp as seeds. The HAp aggregates after two-step phosphoration showed high crystallinity and thermal stability.

[Contents (In Japanese) ] [Contents (In English) ]